I would rather someone hurt my feelings than ignore me at Twitter. Maybe if a person doesn't like someone tweeting them a lot, they should write it in their bio. Twitter is about tweeting. It should not matter how much a person Tweets you. That's what Twitter is about. If I had a million fans and could not answer them all, I would answer 10 fans a day. They would just have to be patient and wait for replies. If there was a specific fan that I would want to communicate with, I would ask that fan for an email address.